Understanding the Role of Family History in Hidradenitis Suppurativa

If you’re living with Hidradenitis Suppurativa (HS), you may have asked yourself:

• “Did I inherit this?”
• “Can I pass this on to my children?”
• “Why does this run in my family?”

These are important—and very real—questions.

The answer is not always simple, but research gives us meaningful insight into how genetics may play a role in HS.

What Does “Genetic” Mean?

When we say a condition is genetic, it means that certain traits or risks can be passed down through families via genes.

However, not all genetic conditions are:

• Guaranteed to be inherited
• Caused by a single gene
• The same for everyone

Some conditions—like HS—are considered genetically influenced, rather than strictly inherited.

What Research Says About HS and Genetics

Research suggests that genetics can play a role in HS, but it is not the only factor.

Key findings:

• About one-third of people with HS report a family history of the condition
• Certain gene mutations have been identified in some families with HS
• These genes are involved in how skin cells and hair follicles function

This means:

• If someone in your family has HS, your risk may be higher
• But having a family history does not guarantee you will develop HS

HS Is More Than Genetics

Even though genetics may increase susceptibility, HS is considered a multifactorial condition.

That means it is influenced by a combination of:

• Genetic predisposition
• Immune system activity
• Hormonal factors
• Inflammation
• Environmental triggers

In other words:
Genes may load the gun—but other factors pull the trigger.

What If HS Runs in Your Family?

If HS appears in multiple family members, you may notice:

• Similar patterns of flare locations
• Age of onset that seems consistent
• Shared triggers or sensitivities

This can feel overwhelming—but it can also provide awareness and early recognition, which is powerful.

The Emotional Side of Genetic Questions

For many, the idea of HS being genetic brings up deeper feelings:

• Guilt (“Did I pass this on?”)
• Fear (“Will my child develop this?”)
• Confusion (“Why me?”)

Let’s gently ground this truth:

• You did not cause this.
• This is not something you chose.

Genetics are complex, and no single person is to blame.

Can HS Be Prevented If It’s Genetic?

Currently, there is no guaranteed way to prevent HS, even if there is a genetic link.

However, awareness allows for:

• Earlier diagnosis
• Better symptom management
• More informed lifestyle choices
• Reduced severity over time

Early recognition can make a meaningful difference in quality of life.

Supporting Your Body Holistically

While you cannot change your genetics, you can support your body in ways that may help reduce inflammation and improve well-being:

• Gentle, consistent skin care
• Managing stress
• Prioritizing rest and recovery
• Supporting overall health through lifestyle choices
• Creating calming self-care rituals

These small, intentional actions can help you feel more in control and supported in your journey.

Final Thoughts: You Are More Than Your Genes

Genetics may be part of the story—but they are not the whole story.

You are not defined by:

• Your diagnosis
• Your DNA
• Your family history

You are defined by how you:

• Care for yourself
• Adapt
• Continue forward

You Are Not Alone in This

Whether HS runs in your family or not, your experience matters.

Through IAHSN and my work, my mission is to provide:

• Education
• Support
• Empowerment

So you can move from uncertainty to understanding—and from understanding to confidence.